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Retrovirus purification: method that conserves envelope glycoprotein and maximizes infectivity

  • McGrath M
  • Witte O
  • Pincus T
  • et al.
Journal of Virology (1978) 25(3) 923-927
DOI: 10.1128/jvi.25.3.923-927.1978
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Abstract

A Sepharose 4B chromatographic method for purification of retroviruses is described which was less time consuming, increased purified virus yields, conserved viral glycoprotein, and increased recovery of biological infectivity in comparison with conventional sucrose gradient ultracentrifugation techniques.

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McGrath, M., Witte, O., Pincus, T., & Weissman, I. L. (1978). Retrovirus purification: method that conserves envelope glycoprotein and maximizes infectivity. Journal of Virology, 25(3), 923–927. https://doi.org/10.1128/jvi.25.3.923-927.1978

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