Effects of Pain, Depression and Quality of Life on Bone Mineral Density in Patients with Fibromyalgia

Abstract

Objective: In this study, we aimed to assess the effects of bone mineral density with fibromyalgia on pain, depression and quality of life. Methods: In this case-control study, 100 women who were diagnosed as FMS and 100 women who were not diagnosed as FMS were included. Visual Analog Scala ( VAS), Fibromyalgia Impact Questionnaire (FIQ) and Hospital Anxiety and Depression Scala (HADS) were used for the patients. Bone mineral density (BMD) of the participants was measured with dual energy x ray absorptiometry (DXA) method. Results: The number of the tender points of the women with fibromyalgia and VAS, FIQ, HAD-A and HAD-D scores were found significantly higher than of the control group (p<0.001). Of the patients with fibromyalgia, 64.3% had anxiety and 59.9% of them had depression. No statistically significant difference was found when the averages of bone mineral density and T-Z scores were compared in two groups (p>0.05). When BMD measurements and HAD-A and HAD-D scores of the fibromyalgia patients were compared; in the L1-L4 region of the patients with anxiety and depression; BMD (mass, T score and Z score) were found respectively lower than of those without anxiety and depression (p=0.011) (p=0.040). Conclusions: The FIQ scores of the patients with low L1-L4 T scores were found higher than of the patients with normal T scores. The L1-L4 region of the patients with anxiety and depression; BMD (mass, T score and Z score) were found respectively lower than of those without anxiety and depression. This study confirmed the concept that FMS is a risk factor for osteoporosis.