Clinical Validation of Plasma-Based Genotyping for RAS and BRAF V600E Mutation in Metastatic Colorectal Cancer: SCRUM-Japan GOZILA Substudy

Yu Aoki; Yoshiaki Nakamura; Tadamichi Denda; Takashi Ohta; Taito Esaki; Manabu Shiozawa; Kensei Yamaguchi; Kentaro Yamazaki; Yu Sunakawa; Takeshi Kato; Naohiro Okano; Hiroya Taniguchi; Taro Sato; Eiji Oki; Tomohiro Nishina; Yoshito Komatsu; Nobuhisa Matsuhashi; Masahiro Goto; Hisateru Yasui; Koushiro Ohtsubo; Toshikazu Moriwaki; Naoki Takahashi; Yosuke Horita; Shogen Boku; Masashi Wakabayashi; Takashi Ikeno; Ryuta Mitani; Mihoko Yuasa; Takayuki Yoshino

Journal ArticleOPEN ACCESS

Clinical Validation of Plasma-Based Genotyping for RAS and BRAF V600E Mutation in Metastatic Colorectal Cancer: SCRUM-Japan GOZILA Substudy

Aoki Y
Nakamura Y
Denda T
et al.

JCO Precision Oncology (2023) (7)

DOI: 10.1200/po.22.00688

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Abstract

Using a large-scale plasma genomic profiling program (SCRUM-Japan GOZILA), we validated ctDNA genotyping for RAS and BRAF V600E in metastatic colorectal cancer comparing with a validated tissue PCR-based testing.

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APA

Aoki, Y., Nakamura, Y., Denda, T., Ohta, T., Esaki, T., Shiozawa, M., … Yoshino, T. (2023). Clinical Validation of Plasma-Based Genotyping for RAS and BRAF V600E Mutation in Metastatic Colorectal Cancer: SCRUM-Japan GOZILA Substudy. JCO Precision Oncology, (7). https://doi.org/10.1200/po.22.00688

Clinical Validation of Plasma-Based Genotyping for RAS and BRAF V600E Mutation in Metastatic Colorectal Cancer: SCRUM-Japan GOZILA Substudy

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