Cutaneous nonepitheliotropic B-cell lymphoma in a Golden retriever

Abstract

The vast majority of cutaneous canine nonepitheliotropic lymphomas are of T cell origin. Nonepithelial B-cell lymphomas are extremely rare. The present case report describes a 10-year-old male Golden retriever that was presented with slowly progressive nodular skin lesions on the trunk and limbs. Histopathology of skin biopsies revealed small periadnexal dermal nodules composed of rather pleomorphic round cells with round or contorted nuclei. The diagnosis of nonepitheliotropic cutaneous B-cell lymphoma was based on histopathological morphology and case follow-up, and was supported immunohistochemically by CD79a positivity.