Effects of tadalafil on the uterine artery of fetal growth restriction

Abstract

Fetal growth restriction (FGR) is the most important cause of perinatal morbidity and mortality during the perinatal period. However, there is no established standard regarding the appropriate delivery time or treatment methods for fetuses with FGR. Reduced uterine arterial blood flow has been reported with FGR; however, if this is improved, then FGR may also be improved. Phosphodiesterase 5 inhibitors have vasodilating actions. When administered to the mother, they may improve FGR by improving fetal placental blood flow through improvements in uterine arterial blood flow.