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N-alkylation of amines under microwave irradiation: Modified eschweiler-clarke reaction

Journal of Chemical Research - Part S (2001) (7) 292-293
DOI: 10.3184/030823401103169810
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Abstract

The N-alkylation of hexahydroazepine and benzylamine is performed under microwave irradiation in the presence of formic acid and different aldehydes or ketones. Good yields were obtained with reactive carbonyl compounds.

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Torchy, S., & Barbry, D. (2001). N-alkylation of amines under microwave irradiation: Modified eschweiler-clarke reaction. Journal of Chemical Research - Part S, (7), 292–293. https://doi.org/10.3184/030823401103169810

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