Distribution of β-lactamases in actinomycetes

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Abstract

The distribution of β-lactamase activities in a collection of actinomycete strains was surveyed. Six of 127 strains were found to produce β-lactamase. This low frequency was in contrast to the case with Streptomyces species. The producing strains were not related phylogenetically. MICs of benzylpenicillin did not correlate with β- lactamase production.

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Ogawara, H., Kawamura, N., Kudo, T., Suzuki, K. I., & Nakase, T. (1999). Distribution of β-lactamases in actinomycetes. Antimicrobial Agents and Chemotherapy, 43(12), 3014–3017. https://doi.org/10.1128/aac.43.12.3014

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