Fullerenol-capped porous silica nanoparticles for pH-responsive drug delivery

Citations of this article
Mendeley users who have this article in their library.


Novel nanocomposite containing fullerenol nanoparticles (FNP) and porous silica nanoparticles (PSNs) was constructed and characterized. The capability of FNP to serve as a pore-capping agent and for entrapping 9-aminoacridine (9-AA) inside the pores of the PSN material was also demonstrated. Nitrogen sorption measurements evidence the successful capping of the silica pores while thermogravimetric analysis of FNP loaded PSN indicates the existence of pore-loaded fullerenol molecules. Higher amount of the drug release was noted by exposing the material to weakly acidic conditions in comparison to physiological pH, which may find application in targeted treatment of weakly acidic tumor tissues.




Knežević, N., Milenković, S., Jović, D., Lazarevic, S., Mrdjanović, J., & Djordjevic, A. (2015). Fullerenol-capped porous silica nanoparticles for pH-responsive drug delivery. Advances in Materials Science and Engineering, 2015. https://doi.org/10.1155/2015/567350

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free