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Induction of alloxan/streptozotocin diabetes in dogs: A revised experimental technique

Laboratory Animals (1993) 27(3) 281-285
DOI: 10.1258/002367793780745426
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Abstract

The diabetic dog represents an excellent model for use in many aspects of diabetic research. The present paper describes, in detail, a reproducible experimental protocol for the successful induction of chemical diabetes in beagles using a combination of the 2 pancreatic beta-cell cytoxic agents alloxan and streptozotocin. © 1993, Royal Society of Medicine Press. All rights reserved.

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Anderson, H. R., Stitt, A. W., Gardiner, T. A., Lloyd, S. J., & Archer, D. B. (1993). Induction of alloxan/streptozotocin diabetes in dogs: A revised experimental technique. Laboratory Animals, 27(3), 281–285. https://doi.org/10.1258/002367793780745426

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