Cationic porphyrin induced a telomeric DNA to G-quadruplex form in water

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Abstract

The formation of the DNA G-quadruplex is induced by the addition of a novel porphyrin carrying four cationic tethers. Circular dichroism spectroscopy reveals that the porphyrin binds to Tetrahymena telomeric repeat to form G-quadruplex under stabilizing-cation-deficient and no buffer conditions.

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Murashima, T., Sakiyama, D., Miyoshi, D., Kuriyama, M., Yamada, T., Miyazawa, T., & Sugimoto, N. (2008). Cationic porphyrin induced a telomeric DNA to G-quadruplex form in water. Bioinorganic Chemistry and Applications, 2008. https://doi.org/10.1155/2008/294756

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