Analysis on gel electrophoresis in biology

Abstract

Gel electrophoresis is one of the basic methods used in modern biological laboratories to separate different compounds in a mixture. It is widely used in analyzing the amino acid sequence in proteins. In the following sections, we will discuss the principles of gel electrophoresis and the current challenges of this technology. Gel electrophoresis is used based on the size, mass, and charge of each particle while the movement of molecules depends on the potential differences in power supply and the channel through which the gel is formed. The composition, properties and indexes of the gel are introduced. The gels, nevertheless, have flaws for scientific studies. In this paper, the mechanism of gel electrophoresis and current challenges confronting it will be discussed as references for further improvement of this technology.