Comparison and Correlation of Cytology, Colposcopy and Histopathology of Premalignant Lesions of Cervix In Rural Women of Barabanki District

Abstract

Aims and Objective: (1)To record the colposcopic and cytological findings of the cases and to compare it with each other in detecting premalignant lesions of cervix taking histopathology as gold standard.(2)To correlate the findings of cytology and colposcopy with histopathology in detecting premalignant lesions of cervix. Materials and Methods: This was a hospital based cross-sectional study conducted at HIMS,Barabanki.The study period was of one year.The study included pap smear samples,colposcopy reports and colposcopy guided cervical biopsy samples of 208 sexually active rural female patients of reproductive age group. Results: Majority of the women were between 31-40 years(59.6%).On PAP smear,ASC-US was found in 5.8% of women,ASC-H in 1.4% of women,LSIL in 6.7% of women and HSIL in 6.2% of women.On colposcopy,LSIL was seen in 26.4% of women and HSIL in 17.8% of women.On histopathological examination,CIN I was seen in 16.8% of women followed by CIN II(8.2%)and CIN III(5.8%).Sensitivity and specificity of PAP smear was 29.7% and 94.4%.Sensitivity and specificity of colposcopy was 85.9% and 74.3%. Conclusion: Pap smear had a poor sensitivity compared to colposcopy but a better specificity than colposcopy.Hence,it may be better to utilise both tests in screening of premalignant lesions of cervix as they complement each other.