Synthesis, Stereochemistry, and Biological Transformation of “Triblattanes”: A Series of Cage-shaped Compounds Possessing D3-Twisted Bicyclo [2.2.2) octane Core as a Common Structural Feature

Abstract

We have been interested in the chemistry of the gyrochiral cage-shaped molecules possessing D3-twisted bicyclo [2. 2. 2]octane molecular framework as a common structural unit, and this article summarizes our recent studies on the synthesis, stereochemistry, and biological transformation of this unique group of cage-shaped molecules on which a generic name “triblattane”1), has been coined to characterize their common structural feature. © 1982, The Society of Synthetic Organic Chemistry, Japan. All rights reserved.