Pharmacognostical, Phytochemical and Pharmacological Evaluation of Mallotus philippensis

Abstract

The present study was aimed at Pharmacognostical, Phytochemical and Pharmacological evaluation of the plant Mallotus Philippinensis family- Euphorbiaceae. Pharmacognostical investigation were carried out by performing organoleptic, microscopical and physicochemical evaluation i.e. ash values, extractive values, moisture content, swelling index, foaming index and foreign matter. The obtained results showed that the moisture content was found to be 1.74%. Similarly swelling index was recorded to be (0.8cm). Foaming index (less than 100). Phytochemical investigation included successive soxhlet extraction, the obtained extractive values were 4.9%, 5.45%, 9.77%, 8.75%, and 4.4% for petroleum ether, chloroform, ethyl acetate, ethanol and distilled water respectively. The preliminary qualitative phytochemical screening revealed the presence of carbohydrates, phenolic compounds, alkaloids, glycosides, flavonoids, steroids, fixed oils and fats. Pharmacological investigation included the Anthelmentic activity by using the Mallotus Philippinensis plant ethyl acetate extract. The 200 mg/kg dose to be found positively in Pharmacological responses. Keywords: Mallotus Philippinensis, Anthelmentic activity, Phytochemical investigation, Pharmacological investigation, Pharmacognostical investigation