On the role of subthreshold currents in the Huber-Braun cold receptor model

Abstract

We study the role of the strength of subthreshold currents in a four-dimensional Hodgkin-Huxley-type model of mammalian cold receptors. Since a total diminution of subthreshold activity corresponds to a decomposition of the model into a slow, subthreshold, and a fast, spiking subsystem, we first elucidate their respective dynamics separately and draw conclusions about their role for the generation of different spiking patterns. These results motivate a numerical bifurcation analysis of the effect of varying the strength of subthreshold currents, which is done by varying a suitable control parameter. We work out the key mechanisms which can be attributed to subthreshold activity and furthermore elucidate the dynamical backbone of different activity patterns generated by this model. © 2010 American Institute of Physics.