Inflaming the Brain

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Abstract

Exactly how cerebrovascular alterations contribute to Alzheimer's disease (AD) is still unknown. Merlini et al. (2019) show that blood-derived fibrinogen leads to dendritic spine elimination and cognitive deficit via microglial CD11b/CD18. Fibrinogen may be a significant contributor to AD pathogenesis.

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Ahn, H. J., Baker, S. K., Norris, E. H., & Strickland, S. (2019, March 20). Inflaming the Brain. Neuron. Cell Press. https://doi.org/10.1016/j.neuron.2019.03.007

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