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Continued Increase of Erythromycin Nonsusceptibility and Clindamycin Nonsusceptibility among Invasive Group A Streptococci Driven by Genomic Clusters, United States, 2018-2019

Clinical Infectious Diseases (2023) 76(3) E1266-E1269
DOI: 10.1093/cid/ciac468
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Abstract

We analyzed 9630 invasive GAS surveillance isolates in the USA. From 2015-2017 to 2018-2019, significant increases in erythromycin-nonsusceptibility (18% vs 25%) and clindamycin-nonsusceptibility (17% vs 24%) occurred, driven by rapid expansions of genomic subclones. Prevention and control of clustered infections appear key to containing antimicrobial resistance.

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Li, Y., Rivers, J., Mathis, S., Li, Z., McGee, L., Chochua, S., … Beall, B. (2023). Continued Increase of Erythromycin Nonsusceptibility and Clindamycin Nonsusceptibility among Invasive Group A Streptococci Driven by Genomic Clusters, United States, 2018-2019. Clinical Infectious Diseases, 76(3), E1266–E1269. https://doi.org/10.1093/cid/ciac468

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