Abstract
In this issue of Blood, Watanabe et al identify a set of 22 genes, including negative regulators of T-cell receptor (TCR) signaling, downregulated with promoter hypermethylation in human T-cell lymphotropic virus-1 (HTLV-1) infected CD41 T cells. The authors then show that the use of hypomethylating agents (HMAs) inhibits adult T-cell leukemia-lymphoma (ATL) growth in xenograft mice.1
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CITATION STYLE
APA
Jolly, C. J., & Pimanda, J. E. (2020, August 13). Titans awake: HMAs for virus-driven ATL. Blood. American Society of Hematology. https://doi.org/10.1182/blood.2020006488
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