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New Water-Soluble Fluorogenic Amine: 7-Aminocoumarin-4-methanesulfonic Acid (ACMS) and Related Substrates for Proteinases

Chemical and Pharmaceutical Bulletin (1988) 36(9) 3496-3502
DOI: 10.1248/cpb.36.3496
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Abstract

The synthesis and properties of a water-soluble fluorogenic amine, 7-aminocoumarin-4-methanesulfonic acid (ACMS, 5) are described. Several peptide amides of 5 were synthesized and examined as new fluorogenic substrates for chymotrypsin, trypsin and related enzymes. © 1988, The Pharmaceutical Society of Japan. All rights reserved.

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Sato, E., Matsuhisa, A., Sakashita, M., & Kanaoka, Y. (1988). New Water-Soluble Fluorogenic Amine: 7-Aminocoumarin-4-methanesulfonic Acid (ACMS) and Related Substrates for Proteinases. Chemical and Pharmaceutical Bulletin, 36(9), 3496–3502. https://doi.org/10.1248/cpb.36.3496

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