New pterosin sesquiterpenes and antitubercular constituents from Pteris ensiformis

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Abstract

Two new pterosin sesquiterpenes, (2S)-13-hydroxypterosin A (1) and (2S,3S)-12-hydroxypterosin Q (2), were isolated from the whole plants of Pteris ensiformis, together with six known compounds. The structures of 1 and 2 were determined through extensive 1D/2D-NMR and MS analyses. Compound 2 exhibited antitubercular activity (MIC 6.25 μg/ml) against Mycobacterium tuberculosis H37Rv in vitro. Copyright © 2013 Verlag Helvetica Chimica Acta AG, Zürich.

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Chen, J. J., Wang, T. C., Yang, C. K., Liao, H. R., Sung, P. J., Chen, I. S., … Chen, J. F. (2013). New pterosin sesquiterpenes and antitubercular constituents from Pteris ensiformis. Chemistry and Biodiversity, 10(10), 1903–1908. https://doi.org/10.1002/cbdv.201300072

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