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An unnatural amino acid dependent, conditional Pseudomonas vaccine prevents bacterial infection

Nature Communications (2024) 15(1)
DOI: 10.1038/s41467-024-50843-7
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Abstract

In this work, authors develop a live vaccine candidate against Pseudomonas aeruginosa using an unnatural amino acid-based auxotrophic strategy. They provide insight on the vaccine’s in vivo safety profile and protection of mice against lethal P. aeruginosa challenge.

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APA

Pigula, M., Lai, Y. C., Koh, M., Diercks, C. S., Rogers, T. F., Dik, D. A., & Schultz, P. G. (2024). An unnatural amino acid dependent, conditional Pseudomonas vaccine prevents bacterial infection. Nature Communications , 15(1). https://doi.org/10.1038/s41467-024-50843-7

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