High yielding microbubble production method

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Abstract

Microfluidic approaches to microbubble production are generally disadvantaged by low yield and high susceptibility to (micro)channel blockages. This paper presents an alternative method of producing microbubbles of 2.6 m mean diameter at concentrations in excess of 30 × 106 mL-1. In this method, the nitrogen gas flowing inside the liquid jet is disintegrated into spray of microbubble when air surrounding this coflowing nitrogen gas-liquid jet passes through a 100 m orifice at high velocity. Resulting microbubble foam has the polydispersity index of 16%. Moreover, a ratio of mean microbubble diameter to channel width ratio was found to be less than 0.025, which substantially alleviates the occurrence of blockages during production.

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Fiabane, J., Prentice, P., & Pancholi, K. (2016). High yielding microbubble production method. BioMed Research International, 2016. https://doi.org/10.1155/2016/3572827

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