Urease operon and urease activity in commensal and disease- Causing nontypeable haemophilus influenza

Abstract

The ure operon was significantly more prevalent in Haemophilus influenzae isolates causing otitis media and chronic obstructive pulmonary disease (COPD)-associated bronchitis than in those from throats of healthy individuals (97% versus 78.1%, P< 0.001). Strains lacking the ure operon are over 8 times more likely to be from the throat than either otitis media or COPD isolates. Copyright © 2013, American Society for Microbiology.