Antimicrobial and Antioxidant Medicinal Plants in Kwau Village and Silau Villlage, Warmare District, Manokwari District, West Papua

Abstract

The purpose of this study was to evaluate antimicrobial and antioxidant of medicinal plants in the villages of Kwau and Siau (Phytochemical, antioxidant, anti-bacterial, antifungal, and toxicity). The bark, roots, and leaves are extracted with methanol to get the extract. Antimicrobial activity against Propionibacterium acnes, Escherichia coli, Streptococcus sobrinus, and Candida albicans was determined by a good diffusion method. The DPPH radical scavenging activity mechanism assayed antioxidant activity. Antimicrobial activity against the bacteria and fungi was determined by the agar well diffusion method. Antioxidant activity was tested by DPPH radical rinsing activity mechanism. Toxicity was determined by the Brine Shrimp Lethality Test method. The results showed that methanol extract showed good activity against acne in only 8 of 13 species, ten species of 13 species for E.colii, three species of 13 species for S. sobrinus and, ten species of 13 species for C. albican at 25-500 ppm of extract tested. The toxicity test showed that 0% of the deaths from Artemia salina Leach shrimp indicated that the absence of harmful compounds was toxic in the sample, meaning that it was very safe to be consumed directly by humans, except for the roots of Spondias cytherea Senn and the bark of Inocarpus fragiferua Fosk.