Standardization of jatyadi ghrita by hptlc method

Abstract

Standardization of herbal formulation is essential in order to asses the quality of drugs for therapeutic value. According to an estimate of world Health Organization (WHO) nearly 80% of population of developing countries relies on traditional medicine. Jatyadi Ghrita was found in authentic book like Ayurvedic formulary of India and used as a topical product prescribed for the treatment of all kind of wounds of the body. It is a polyherbal preparation containing eleven ingredients. In this research paper an attempt has been made to develop standardization method for some of the ingredients of Jatyadi Ghrita. Quantitative estimation and stability was done by HPTLC methods using Glycyrrhetinic acid, Ursolic acid, Karanjin, Curcumin, Berberine and kutkin as markers which are major constituents of formulation. A standard laboratory reference sample of Jatyadi Ghrita and four marketed samples were evaluated as per methods. Data has been provided to demonstrate applicability of the methods to standardization of Jatyadi Ghrita.