Abstract
A 13 year old girl who had had transient neonatal diabetes developed permanent diabetes. She had raised fasting insulin concentrations suggestive of insulin resistance with a suboptimal insulin response to glucose loading. Both her mother and sister had profound insulin resistance; neither had clinical diabetes. This is the first time inherited insulin resistance has been implicated in the pathogenensis of permanent diabetes developing after transient neonatal diabetes.
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Shield, J. P. H., & Baum, J. D. (1995). Transient neonatal diabetes and later onset diabetes: A case of inherited insulin resistance. Archives of Disease in Childhood, 72(1), 56–57. https://doi.org/10.1136/adc.72.1.56
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