Granulocyte transfusion therapy 2006: The comeback kid?

Abstract

There has been an increased interest in the use of therapeutic granulocyte transfusion in recent years because premedication of donors with granulocyte colony stimulating factors produces much higher doses of granulocytes for transfusion. Other factors which influence the outcome of transfusion include the types of infection being treated, the likelihood of recipient marrow recovery and recipient alloimmunization. This review provides a historical perspective on these issues.