Antidepressant activity of patchouli alcohol microcapsule

Abstract

Patchouli alcohol is an essential oil compound which obtained by fractional distillation of patchouli oil (Pogostemon cablin Benth). Patchouli alcohol has several benefits in aromatheraphy field. Patchouli alcohol is useful for reduce depression by breathing is steam. The essential oil is a sensitive and susceptive material towards high temperature, oxidation, UV light, and humidity which are able to cause the oxidative damage. Encapsulation can be the way to resolve this problem. Maltodextrin and gum arabic are kind of good catalysts in the essential oil encapsulation. In this research will be done patchouli alcohol encapsulation by using freeze drying method with maltodextrin, gum arabic and tween 80 catalysts as emulsifier. Patchouli alcohol that will be used is coming from the distillation with the content of 42.37% which will be tested its antidepressant to mice further. The test results of the best antidepressant was on microcapsule powder with the variation of (1 g maltodextrin: 1 g gum arabic: 3 g patchouli alcohol).