Abstract
Summary: We present an approach to statistically pinpoint differentially expressed proteins that have quantitation values near the quantitation threshold and are not identified in all replicates (marginal cases). Our method uses a Bayesian strategy to combine parametric statistics with an empirical distribution built from the reproducibility quality of the technical replicates. © The Author 2010. Published by Oxford University Press. All rights reserved.
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CITATION STYLE
Carvalho, P. C., Fischer, J. S. G., Perales, J., Yates, J. R., Barbosa, V. C., & Bareinboim, E. (2011). Analyzing marginal cases in differential shotgun proteomics. Bioinformatics, 27(2), 275–276. https://doi.org/10.1093/bioinformatics/btq632
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