Synthesis of Strontium Substituted Hydroxyapatite Coating on Titanium Via Hydrothermal Method

Abstract

In this study, strontium substituted hydroxyapatite (SrHA) was successfully deposited onto etched titanium substrates in H2SO4 and HCl solution. The deposition was achieved by hydrothermal method by immersing the substrates in a solution containing Ca(NO3)2.4H2O, NH4H2PO4, and 5% Sr(NO3)2, followed by heating at 200°C for 12 hours. X-ray diffraction (XRD) analysis confirmed that all SrHA coatings exhibited a crystalline hydroxyapatite structure. Field-emission scanning electron microscopy (FE-SEM) revealed that the microstructure of the SrHA coatings exhibited. Bioactivity and in vitro biocompatibility testing of the SrHA-coated titanium substrates using SBF solution and baby hamster kidney (BHK) cells demonstrated positive results.