Time-related changes in prevalence of chronic heart failure and diabetes mellitus in Nizhny Novgorod Region between 2000 and 2017

Abstract

Aim. To determine time-related changes in prevalence, morbidity, and all-cause mortality of patients with CHF depending on the presence of DM in a representative sample of Nizhny Novgorod Region. Materials and methods. In 1998, a representative sample of Nizhny Novgorod Region was created, which included 1922 respondents. From 2000 through 2017, this sample was evaluated three times. Patients with CHF and DM were studied. Results. For 17 years, prevalence of NYHA FC IV CHF increased from 6.88 to 9.1 % (p=0.04). Prevalence of NYHA FC III-IV CHF increased considerably from 1.2 % to 4.8 % (p<0.001). Morbidity of CHF patients increased from 10.8 to 16.4 per 1000 (p=0.02) and morbidity of DM patients increased from 3.7 to 6.6 per 1000 (p=0.03). DM significantly worsened the life prediction, particularly for patients with NYHA FC III-IV CHF. Conclusion. Prevalence of CHF is growing. Morbidity and all-cause mortality depend on the presence of DM and CHF FC severity. Risk for all-cause mortality increases following CHF decompensation no matter of the DM presence.