Superovulation in mice in relation to their age.

Abstract

Superovulation in mice is most likely to be successful if they are treated at the age of 20-32 days. Both the number of ovulations and the quality of the embryos are significantly better in comparison with superovulated older mice (32-60 days). In this investigation the production of normally developed embryos in young mice of 20-32 days old was 28.7 per superovulated animal and 11.3 or 14.0 in the groups of older mice respectively (32-46 days and 46-60 days).