Familial glioblastoma with hepatic focal nodular hyperplasia

Abstract

Two siblings succumbed to glioblastoma multiforme, associated with hepatic focal nodular hyperplasia and cafe‐au‐lait spots. One sibling had syndactyly and multiple colonic polyps, while the other had an angiomatous malformation in the brain. Their mother died of myasthenia gravis. The findings suggest a hamartomatous syndrome of malformations that predisposes to brain tumors. Copyright © 1976 American Cancer Society