Influence of autophagy on the efficacy of radiotherapy

89Citations
Citations of this article
76Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Autophagy is an important catabolic process in which cells digest and recycle their own cytoplasmic contents for maintaining cellular homeostasis. Interestingly, autophagy could play both pro-death and pro-survival roles in influencing the development of cancer via various signal pathways. As radiotherapy is one of the main treatment modalities for cancer, we reviewed the effect of autophagy modulations on radiosensitivity and radiotherapy efficacy in various cancer types. The future development of autophagy modifications for improving radiotherapy efficacy and cancer prognosis will also be discussed.

Cite

CITATION STYLE

APA

Tam, S. Y., Wu, V. W. C., & Law, H. K. W. (2017, March 21). Influence of autophagy on the efficacy of radiotherapy. Radiation Oncology. BioMed Central Ltd. https://doi.org/10.1186/s13014-017-0795-y

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free