OBJECTIVE: To compare the enzyme activity of different presentations of papain solution to validate in-house preparations. METHODS: Two papain solutions were prepared, and the third presentation was a commercial solution. Tests were carried out with samples of red cells typed as weak RhD. RESULTS: In-house prepared papain solutions showed similar enzyme reactivity, and statistically no differences compared to the enzyme activity of the commercial solution. CONCLUSION: Evaluating the cost-benefit ratio, the in-house prepared papain solutions present more economic advantages, and can be incorporated into immunohematological routines as a way to cope with periods of financial crisis and cost-containment policies.
CITATION STYLE
Santis, L. P. D., Garcia, P. C., Secco, V. N. D. P., Ferreira, R. R., & Deffune, E. (2019). Applicability of papain solutions in immunohematology. Einstein (Sao Paulo, Brazil), 17(2), eAO4328. https://doi.org/10.31744/einstein_journal/2019AO4328
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