Application of particle measurement technology in process intensification

Abstract

The competitive pressure in the chemical industry makes it necessary to take measures that enable processes to be drastically improved in order to remain competitive also in the future. For the development and implementation of such process-intensive measures, it is expedient to perform a complete analysis of the process of interest. This approach is demonstrated using a size reduction process for a particulate active substance as an example. Correlations between the dispersion characteristics and quality characteristics of the product were found using two complementary methods of particle measurement technology, ultrasonic spectroscopy and laser diffraction. These methods make it possible to analyze the efficiency of the comminution apparatuses, but also of the processes. Ultrasonic spectroscopy can be used as a measurement method for local process control. © 2008 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.