Benast Atins A And B, New Inhibitors Of Glutathione S-Transferase, Produced By Streptomyces Sp. Mi384-Df12 Ii. Structure Determination Of Benast Atins A And B

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Abstract

Benastatins A and B, new inhibitors of glutathione S-transferase, have been isolated from the culture broth of Streptomyces sp. MI384-DF12. By X-ray crystallography, benastatin A was determined to be 8,13-dihydro-1,7,9,1 l-tetrahydroxy-13-dimethyl-8-oxo-3-pentyl-benzo[a]naphtha-cene-2-carboxylic acid. The structure of benastatin B was elucidated by NMR studies. © 1992, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

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Aoyama, T., Naganawa, H., Muraoka, Y., Nakamura, H., Takeuchi, T., aoyagi, T., & Iltaka, Y. (1992). Benast Atins A And B, New Inhibitors Of Glutathione S-Transferase, Produced By Streptomyces Sp. Mi384-Df12 Ii. Structure Determination Of Benast Atins A And B. Journal of Antibiotics, 45(9), 1391–1396. https://doi.org/10.7164/antibiotics.45.1391

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