Enrofloxacinium oxalate

Abstract

The title salt, 2C19H23FN3O3+-C2O42- {systematic name: bis-[4-(3-carboxy-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinolin-7-yl)- 1-ethylpiperazin-1-ium] oxalate}, crystallizes with two independent monocations (A and B) and an oxalate dianion (C) in the asymmetric unit. The piperazinium ring in both the cations adopts a slightly disordered chair conformation. The dihedral angles between the mean planes of the cyclopropyl ring and the 10-membered quinoline ring are 50.6(5)° (A) and 62.2(5)° (B). In each of the cations, a single O - HO intramolecular hydrogen bond is observed. In the crystal, the oxalate anions interact with the cations through N - HO hydrogen bonds and weak C - HO interactions, forming R 22(8) graph-set ring motifs. Weak C - HF interactions along with further C - HO interactions are observed between the cations, forming zigzag chains along [001]. In addition, π-π stacking interactions are observed with centroid-centroid distances of 3.5089(13), 3.5583(13), 3.7900(13) and 3.7991(13)Å. © Yamuna et al. 2014.