A strong case for viral genetic factors in HIV virulence

Abstract

HIV infections show great variation in the rate of progression to disease, and the role of viral genetic factors in this variation had remained poorly characterized until recently. Now a series of four studies [1-4] published within a year has filled this important gap and has demonstrated a robust effect of the viral genotype on HIV virulence © 2011 by the authors; licensee MDPI, Basel, Switzerland.