Interference based aberration-free chromatic stimulator for human myopia research

Abstract

Previous studies showed an impact of the light spectrum on ocular growth. It is unclear whether the eye reacts to the light chromaticity or to the defocus induced by the longitudinal chromatic aberration (LCA). This study investigated the influence of narrow-band aberration-free light on axial length as an indicator for eye growth. Using a laser-interference exposure setup, 18 healthy eyes were stimulated with aberration-free short-wavelength light (450 ± 5 nm), mid-wavelength light (550 ± 5 nm) and long-wavelength light (650 ± 5 nm) for 20 min. Axial length was measured before and after the exposure in the test eye and control eye. No statistically significant axial length changes from baseline were observed after exposure to narrow-band aberration-free light (all p > 0.05). Axial length responses did not differ significantly between chromatic conditions or test and control eye (all p > 0.05). The study suggests that light chromaticity does not present a signal for ocular growth under the tested conditions without the additional information of LCA-induced defocus.