Helicobacter pylori infection in neonatal mice prevents allergic asthma

Abstract

In this preclinical study, the authors hypothesised that neonatal infection with an immonomodulatory pathogen such as Helicobacter pylori provides protection from allergic airway inflammation and hyper-responsiveness seen in allergic asthma. C57BL/6 mice were orally infected with H pylori at 6 days (neonatal) and 6 weeks (adults) after birth. Infected and non-infected mice underwent …