Decarboxylative cross-coupling of aryl tosylates with aromatic carboxylate salts

Abstract

(Figure Presented) A bimetallic copper/palladium catalyst system is disclosed that enables the use of tosylates as carbon electrophiles in decarboxylative coupling reactions. A variety of aromatic carboxylate salts, regardless of their substitution pattern, have been coupled with these inexpensive and readily available electrophiles to give the corresponding biaryl compounds in good yields (see scheme). © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.