One pot synthesis of some new 2-hydrazino-[1,3,4]thiadiazepino [7,6-b]quinolines under microwave irradiation conditions

Abstract

An efficient and convenient procedure has been developed for the synthesis of 2-hydrazino-[1,3,4]thiadiazepino[7,6-b]quinolines (2a-h) in good yields. They have been achieved by the reaction between corresponding 2-chloro-3-formyl- quinoline and carbidimide in specially desighned microwave oven for organic synthesis in unsealed borosil vessel in presence of p-TsOH and dimethylformamide. The structure of new compounds has been evaluated on the basis of analytical, IR, 1H NMR and mass spectral data. ©ARKAT.