Kinetics of enolisation of acetophenone and p-bromoacetophenone: Comparative studies

Abstract

Biomolecules (Amino Acids) have been used as catalysts for the study of kinetics involved in enolisation of acetophenone and p-bromoacetophenone, and comparative study has been carried out. The process of enolisation has been studied by halogenation reactions using iodine. The stoichiometery was determined in each case and the kinetic reactions have been carried out to study the effect of catalyst and temperature. The enolisation process has been investigated as a bimolecular reaction. The rate of enolisation was of the order p-Bromoacetophenone > Acetophenone depending on the type of substituent. The process studies follow Ar-rhenius equation. Values for various thermodynamic parameters like entropy (ΔS≠) and enthalpy (ΔH≠) were found to be-2.126 e.u. &-10.88 e.u. and 19.06 kcal.mol-1 & 19.01 kcal.mol-1 for acetophenone and p-bromoacetophenone, respectively. © 2013 BCREC UNDIP. All rights reserved.