Polymorphisms within 5′ end of the Neuregulin 1 gene are genetically associated with schizophrenia in the Chinese population

Abstract

The 8p gene Neuregulin 1, which is one of the glial growth factors expressed during neurodevelopment and in the adult CNS, has recently been identified as a susceptibility gene for schizophrenia by linkage and LD mapping studies in the Icelandic and Scottish population. In the present work, the authors provide independent statistical support for the previous findings that schizophrenia is associated with the 5′ end of the Neuregulin 1 gene.