MSCs can be a double-edged sword in tumorigenesis

17Citations
Citations of this article
23Readers
Mendeley users who have this article in their library.

Abstract

Mesenchymal stem cells (MSCs) have been used to treat various diseases including Alzheimer’s disease and cancer. In particular, the immunomodulatory function of MSCs plays a major role in cancer therapy using stem cells. However, MSCs exert promotive and inhibitory effects on cancer. The immunomodulatory effects of MSCs in the tumor microenvironment (TME) are ambiguous, which is the primary reason for the different outcomes of MSCs therapies for tumors. This review discusses the use of MSCs in cancer immunotherapy and their immunomodulatory mechanisms in cancers.

Cite

CITATION STYLE

APA

Zhang, L., Xiang, J., Zhang, F., Liu, L., & Hu, C. (2022, November 10). MSCs can be a double-edged sword in tumorigenesis. Frontiers in Oncology. Frontiers Media S.A. https://doi.org/10.3389/fonc.2022.1047907

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free