Convenient preparation of 1-amidoindenes

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Abstract

Lewis acid-catalyzed α-amidoalkylation of enolizable aldehydes with N-(α-benzotriazolyl-α-arylalkyl)amides followed by intramolecular Friedel - Crafts cyclization provides a convenient route to 2-substituted 1-amidoindenes.

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Katritzky, A. R., Denisko, O. V., & Busont, S. (2000). Convenient preparation of 1-amidoindenes. Journal of Organic Chemistry, 65(23), 8066–8068. https://doi.org/10.1021/jo0005565

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