Abstract
adhesion molecule-1, thrombospondin, and histidine-rich protein causing microcirculatory obstruction. [3] Disseminated intravascular coagulation is also a contributing factor in malaria-related SPG and is rarely associated with significant bleeding. [4] Management of SPG in malaria is supportive. There is no specific treatment for SPG per se and routine use of antiplatelets or anticoagulants is not indicated. The mortality rate of SPG is almost 35% and 70%-90% patients might need amputation after line of demarcation develops. [5] references 1. McGouran RC, Emmerson GA. Symmetrical peripheral gangrene. Br Heart J 1977;39:569-72. 2. Phillips RE, Looareesuwan S, Warrell DA, Lee SH, Karbwang J, Warrell MJ, et al. The importance of anaemia in cerebral and uncomplicated falciparum malaria: Role of complications, dyserythropoiesis and iron sequestration. Q J Med 1986;58:305-23.
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Mehrpour, O. (2017). Cardiogenic shock: The main cause of mortality in acute aluminum phosphide poisoning. Indian Journal of Critical Care Medicine, 21(4), 246–247. https://doi.org/10.4103/ijccm.ijccm_97_17
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