Rapid microfluidic immunoassays of cancer biomarker proteins using disposable inkjet-printed gold nanoparticle arrays

Abstract

Off-line amplification: A low-cost inkjet-printed gold nanoparticle immu-noarray was integrated into a microfluidic device for multiple protein determinations. The use of heavily labeled magnetic beads allows optimization either for ultrasensitive detection of biomarker proteins (low fg mL -1 levels) or for rapid 8 min assays within clinically relevant detection ranges. © 2013 The Authors.