Correlation of Antihypertensive Drugs Ca-Antagonist Amlodipine with Xerostomia

Abstract

Xerostomia is defined as a subjective complaint of dry mouth. Interestingly, patients complaining of dry mouth often have no objective signs of decreased salivation and their symptoms vary. May be secondary to qualitative and/or quantitative factors. changes in the composition of saliva. Normal stimulated salivary flow averages 1.5-2.0 ml/min while unstimulated salivary flow is about 0, 3-0.4 ml/min. This review aimed to determine the correlation between the Ca antagonist of the antihypertensive drug (Amlodipine) and xerostomia through a literature review conducted by researchers which was used as a reference for making this literature review. Data were obtained by data collection methods related to the study being studied and analyzed descriptively. Several studies show that there are differences in prevalence between genders and xerostomia appears to increase with age. A possible explanation is that older people are at risk due to some xerogenic medications for their chronic conditions and this may cause an overall decrease in the rate of unstimulated saliva flow. Xerostomia remains a common unresolved complaint especially among the geriatric population, despite efforts for medical or dental consultation. It was concluded that Ca-Antagonist antihypertensive drugs (amlodipine) were associated with xerostomia.